Megacaryoblastic acute leukemia: understanding the mechanisms involved to improve management

Megacaryoblastic acute leukemia

Megacaryoblastic acute leukaemias are infantile blood cancers that are too resistant to treatments. The researchers wish to explore the molecular mechanisms at the heart of the development of these cancers to discover new therapeutic targets. To do this, they are developing very advanced cell models to explore the formation of tumors. ┬áThis research is led by Thomas Mercher and his team “Genetics and modeling of childhood leukemia” at the Gustave Roussy Institute in Villejuif. Megacaryoblastic acute leukemia: a specific entity Thomas Mercher and his team are interested in a particular…

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Heal 2 cancers out of 3 : we, we believe!

Heal 2 cancers out of 3

What is leukemia? The different forms Risk factors Symptoms and diagnosis – acute leukemias Symptoms and diagnosis – chronic leukemias Treatments The graft Living with and after leukemia in an adult The research The ARC Foundation and adult leukemia research Useful contacts ┬áSymptoms and diagnosis of acute adult leukemia The leukemia acute occur suddenly and quickly diagnosed. The main symptoms Most often, acute leukemia settles abruptly in a few days without warning signs. It may sometimes remain silent but usually results in rapid deterioration of the general condition and an…

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Leukemia: What is it?


The leukemia is a cancer of tissues responsible for the formation of blood, that is to say of immature blood cells in the bone marrow (= soft, spongy material in the center of most bones). The disease usually begins with an abnormality in the formation of blood cells in the bone marrow. Abnormal cells (or leukemic cells ) multiply and become more numerous than normal cells, thus preventing their proper functioning. Types of leukemia There are several types of leukemia. They can be classified according to the speed of the…

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